Partial breast irradiation with CyberKnife after breast conserving surgery: a pilot study in early breast cancer.

ABSTRACT:

Background

Local recurrences after breast conserving treatment are mainly close to the original tumor site, and as such shorter fractionation strategies focused on and nearest mammary gland, i.e. accelerated partial breast irradiation (APBI), have been developed. Stereotactic APBI has been attempted, although there is little experience using CyberKnife (CK) for early breast cancer.

Methods

This pilot study was designed to assess the feasibility of CK-APBI on 20 evaluable patients of 29 eligible, followed for 2 years. The primary endpoint was acute/sub-acute toxicity; secondary endpoints were late toxicity and the cosmetic result.

Results

Mean pathological tumor size was 10.5 mm (±4.3, range 3-18), 8 of these patients were classified as LumA-like, 11 as LumB-like, and

SUBMITTER: Lozza L 

PROVIDER: S-EPMC5865347 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature