Endocrine Disorders in Primary Mitochondrial Disease.

ABSTRACT:

Context

Endocrine disorders are common in individuals with mitochondrial disease. To develop evidence-based screening practices in this high-risk population, updated age-stratified estimates of the prevalence of endocrine conditions are needed.

Objective

To measure the point prevalence of selected endocrine disorders in individuals with mitochondrial disease.

Design setting and patients

The North American Mitochondrial Disease Consortium Patient Registry is a large, prospective, physician-curated cohort study of individuals with mitochondrial disease. Participants (n = 404) are of any age, with a diagnosis of primary mitochondrial disease confirmed by molecular genetic testing.

Main outcome measures

Age-specific prevalence of diabetes mellitus (DM), abnormal gr

SUBMITTER: Al-Gadi IS 

PROVIDER: S-EPMC5865537 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature