Trigger pSA predicting recurrence from positive choline PET/CT with prostate cancer after initial treatment.

ABSTRACT:

Purpose

To assess the relationship between the diagnostic accuracy of Choline positron emission tomography/computed tomography (PET/CT) and the trigger prostate-specific antigen (PSA) level in patients with a biochemical recurrence of prostate cancer.

Materials and methods

A meta-analysis was conducted to synthesize data across multiple studies.

Results

The pooled sensitivity and specificity of choline PET/CT were 82% (95% Confidence Interval (CI):80-84%) and 92% (95%CI: 90-93%), respectively. The pooled sensitivity and specificity of ¹⁸F-choline PET/CT were 81% (95%CI: 78-84%) and 90% (95%CI: 85-93%), respectively. The pooled sensitivity and specificity of ¹¹C-choline PET/CT were 83% (95% CI: 80-86%) and 92% (95% CI: 90-94%), respectively. The p

SUBMITTER: Wei J 

PROVIDER: S-EPMC5865695 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature