Structural and functional analyses of the optic nerve and lateral geniculate nucleus in glaucoma.

ABSTRACT:

Purpose

To analyze the correlation between structural characteristics of intraorbital optic nerve (ION) and lateral geniculate nucleus (LGN) measured by 3-Tesla magnetic resonance imaging (3T MRI), and the severity of glaucomatous damage.

Methods

In this cross-sectional study, 41 glaucoma patients and 12 age- and sex-matched controls underwent standard automated perimetry (SAP) and frequency doubling technology (FDT) as functional evaluation; optic disc stereophotograph, spectral-domain optical coherence tomography (OCT) and confocal scanning laser tomography as ocular structural evaluation; and 3T MRI. Structure-structure and structure-function correlation were performed using bootstrap resampling method for clustered data.

Results

The ION mean diameter and cross-sec

SUBMITTER: Furlanetto RL 

PROVIDER: S-EPMC5865716 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature