Smoking intensity and bladder cancer aggressiveness at diagnosis.

ABSTRACT:

Objective

To explore the relation between cigarette smoking intensity and bladder cancer aggressiveness at first diagnosis.

Methods

Patients diagnosed with urinary bladder cancer (BC) between 1995-2011 under the age of 75 years were retrospectively identified from the Netherlands Cancer Registry and invited for a study on genetic and lifestyle risk factors for BC. Information on patients' self-reported smoking history was retrieved by means of a postal questionnaire. Tumors were stratified regarding the risk of progression defined by tumor stage and grade. Multinomial logistic regression was used to analyze the relation between smoking intensity and aggressiveness of the tumor.

Results

The UBC study population comprised 323 (17.4%) never smokers, 870 (46.8%) former ci

SUBMITTER: Barbosa ALA 

PROVIDER: S-EPMC5865728 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature