Dynamic expression analysis of armc10, the homologous gene of human GPRASP2, in zebrafish embryos.

ABSTRACT: G protein‑coupled receptor‑associated sorting protein 2 (GPRASP2), a member of the GASP family, has been reported to be involved in the modulation of transcription. However, few studies have revealed the role of GPRASP2 in the development and progression of diseases. As a model organism, zebrafish have been widely used to investigate human diseases. In the present study, zebrafish armadillo repeat‑containing 10 (armc10), an orthologous gene of human GPRASP2 was identified, and the spatial and temporal expression patterns of armc10 in zebrafish during early embryonic development were revealed. Bioinformatics analyses showed that ARMC10 protein sequences were highly conserved. Reverse transcription polymerase chain reaction analysis and whole mount in situ hybridization revealed that zebrafi

SUBMITTER: Liu C 

PROVIDER: S-EPMC5865771 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature