Unknown

Dataset Information

0

Expression of long non?coding RNAs in human bone marrow mesenchymal stem cells co?cultured with human amnion?derived mesenchymal stem cells.

ABSTRACT: Long non?coding RNAs (lncRNAs) serve a critical role in various biological processes including cell growth, transcriptional regulation and differentiation. Previous studies have demonstrated that human amnion?derived mesenchymal stem cells (HAMSCs) possess the potential to promote proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMSCs). However, little is known about the roles of lncRNAs in these mechanisms. The present study investigated the expression of lncRNAs in HBMSCs co?cultured with HAMSCs to study their involvement in the mechanism of osteogenic differentiation. RNA sequencing was used to compare the lncRNA expression pro?les of HBMSCs co?cultured with or without HAMSCs during osteogenic differentiation. A total of 339 differentially expressed lncRNAs were identi?ed [log2 (fold change)>2.0 or

SUBMITTER: Wang J 

PROVIDER: S-EPMC5865784 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Expression of long non‑coding RNAs in human bone marrow mesenchymal stem cells co‑cultured with human amnion‑derived mesenchymal stem cells.

Wang Jingjing J   Miao Jing J   Meng Xin X   Chen Ning N   Wang Yuli Y  

Molecular medicine reports 20170912 5

Long non‑coding RNAs (lncRNAs) serve a critical role in various biological processes including cell growth, transcriptional regulation and differentiation. Previous studies have demonstrated that human amnion‑derived mesenchymal stem cells (HAMSCs) possess the potential to promote proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMSCs). However, little is known about the roles of lncRNAs in these mechanisms. The present study investigated the expression  ...[more]

Similar Datasets

Unknown Potential functions of long non?coding RNAs in the osteogenic differentiation of human bone marrow mesenchymal stem cells.
| S-EPMC6297760 | biostudies-literature
Unknown Human amnion-derived mesenchymal stem cells promote osteogenic differentiation of lipopolysaccharide-induced human bone marrow mesenchymal stem cells via ANRIL/miR-125a/APC axis.
| S-EPMC7791649 | biostudies-literature
Unknown Comparable osteogenic capacity of mesenchymal stem or stromal cells derived from human amnion membrane and bone marrow.
| S-EPMC5851966 | biostudies-literature
Unknown Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells.
| S-EPMC6097446 | biostudies-literature
Unknown Human amnion-derived mesenchymal stem cells promote osteogenic and angiogenic differentiation of human adipose-derived stem cells.
| S-EPMC5636128 | biostudies-literature
Unknown The immunosuppressive capacity of human mesenchymal stromal cells derived from amnion and bone marrow.
| S-EPMC5613701 | biostudies-other
Unknown Bisphosphonates induce the osteogenic gene expression in co-cultured human endothelial and mesenchymal stem cells.
| S-EPMC3916115 | biostudies-literature
Unknown Identification of long non?coding RNAs expressed during the osteogenic differentiation of human bone marrow?derived mesenchymal stem cells obtained from patients with ONFH.
| S-EPMC7521548 | biostudies-literature
Unknown Osteogenic and angiogenic potentials of monocultured and co-cultured human-bone-marrow-derived mesenchymal stem cells and human-umbilical-vein endothelial cells on three-dimensional porous beta-tricalcium phosphate scaffold.
| S-EPMC3508299 | biostudies-literature
Unknown From cytogenomic to epigenomic profiles: monitoring the biologic behavior of in vitro cultured human bone marrow mesenchymal stem cells.
| S-EPMC3580477 | biostudies-literature