Publishing 13C metabolic flux analysis studies: a review and future perspectives.

ABSTRACT: (13)C-Metabolic flux analysis ((13)C-MFA) is a powerful model-based analysis technique for determining intracellular metabolic fluxes in living cells. It has become a standard tool in many labs for quantifying cell physiology, e.g., in metabolic engineering, systems biology, biotechnology, and biomedical research. With the increasing number of (13)C-MFA studies published each year, it is now ever more important to provide practical guidelines for performing and publishing (13)C-MFA studies so that quality is not sacrificed as the number of publications increases. The main purpose of this paper is to provide an overview of good practices in (13)C-MFA, which can eventually be used as minimum data standards for publishing (13)C-MFA studies. The motivation for this work is two-fold: (1) curren

SUBMITTER: Crown SB 

PROVIDER: S-EPMC5866723 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature