Pre-admission proteinuria impacts risk of non-recovery after dialysis-requiring acute kidney injury.

ABSTRACT: Renal recovery after dialysis-requiring acute kidney injury (AKI-D) is an important clinical and patient-centered outcome. Here we examined whether the pre-admission proteinuria level independently influences risk for non-recovery after AKI-D in a community-based population. All adult members of Kaiser Permanente Northern California who experienced AKI-D between January 1, 2009 and September 30, 2015 were included. Pre-admission proteinuria levels were determined by dipstick up to four years before the AKI-D hospitalization and the outcome was renal recovery (survival and dialysis-independence four weeks and more) at 90 days after initiation of renal replacement therapy. We used multivariable logistic regression to adjust for baseline estimated glomerular filtration rate (eGFR), age, sex,

SUBMITTER: Lee BJ 

PROVIDER: S-EPMC5866747 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature