Cerebrospinal fluid Lyme multiplex assay results are not diagnostic in horses with neuroborreliosis.

ABSTRACT:

Background

The accuracy of the Lyme multiplex assay for the diagnosis of neuroborreliosis in horses is unknown.

Hypothesis/objectives

To describe Lyme multiplex results in horses with a postmortem diagnosis of neuroborreliosis. The hypothesis was that paired serum and cerebrospinal fluid (CSF) results and a CSF : serum ratio would allow differentiation of horses with neuroborreliosis from those with other neurologic diseases.

Animals

Ninety horses that had neurologic examinations, serum and CSF Lyme multiplex analyses, and postmortem examination of the nervous system performed.

Methods

Retrospective study. Data collected included signalment, ante- and postmortem diagnoses, and serum and CSF Lyme multiplex results. The CSF : serum ratio was calculated by dividin

SUBMITTER: Johnson AL 

PROVIDER: S-EPMC5866998 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature