Characterization of adherence and persistence profile in a real-life population of patients treated with adalimumab.

ABSTRACT:

Aims

Published data on long-term adherence and persistence with adalimumab (Humira^® ) in clinical practice are scarce and often limited to selected patient populations. This study assessed adherence with adalimumab across different indications and identified correlates and outcomes of poor adherence.

Methods

We analysed data originating from the electronic database of Maccabi Healthcare Services (MHS) that includes 2.1 million enrolees. We randomly selected patients with at least one dispense of adalimumab since it was included in the local health basket in Israel in 2008 until the end of 2013. Patients with the following indications (n = 1339) were included: Crohn's disease (CD), ulcerative colitis (UC), rheumatoid arthritis (RA), psoriatic arthritis (PSA), ankyl

SUBMITTER: Gendelman O 

PROVIDER: S-EPMC5867139 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature