Long-term metabolic risk for the metabolically healthy overweight/obese phenotype.

ABSTRACT:

Background/objectives

The clinical relevance of the metabolically healthy overweight/obese (MHO) phenotype is controversial and the relationships between weight change and the development of cardiometabolic risk factors is unknown. Therefore, we aim to: (1) Assess the long-term risk of developing one or more components of the metabolic syndrome in MHO adults compared with metabolically healthy normal weight (MHNW); (2) Evaluate risk of a composite of death, cardiovascular disease (CVD), and risk of developing type 2 diabetes between adults defined according to baseline body mass index and metabolic health.

Subjects/methods

Retrospective cohort study of adults 18-65 years of age seen at our institution between 1998 and 2000 who lived in Olmsted County. Metabolically healthy w

SUBMITTER: Espinosa De Ycaza AE 

PROVIDER: S-EPMC5867190 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature