Lifestyle factors and subsequent ischemic heart disease risk after hematopoietic cell transplantation.

ABSTRACT:

Background

The objective of this study was to evaluate whether modifiable cardiovascular risk conditions and lifestyle factors were temporally associated with an increased risk for ischemic heart disease and overall mortality in a cohort of hematopoietic cell transplantation (HCT) survivors.

Methods

HCT recipients who had survived for ≥1 year, were ≥20 years old, and had undergone transplantation between 1970 and 2010 at a transplant referral center were surveyed in 2010-2011 about cardiovascular health and lifestyle factors (n = 3833). Respondents (n = 2360 [61.6%]) were followed to 2016 for incident ischemic heart disease and overall mortality.

Results

Among the 2360 transplant survivors (median age at the baseline survey, 55.9 years; median time since transplantati

SUBMITTER: Leger KJ 

PROVIDER: S-EPMC5867247 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature