Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid.

ABSTRACT:

Background

The diagnosis of active pulmonary tuberculosis (TB) remains a challenge in clinic, especially for sputum negative pulmonary TB. Bronchoalveolar lavage fluid (BALF) has higher sensitivity than sputum for detection of Mycobacterium tuberculosis (Mtb). However, bronchoscopy is invasive and costly, and not suitable for all patients. In order to make TB patients get more benefit from BALF for diagnosis, we explore which indicator might be used to optimize the choice of bronchoscopy.

Methods

A total of 1539 sputum-smear-negative pulmonary TB suspects who underwent bronchoscopy were recruited for evaluation. The sensitivity, specificity and accuracy of Mtb detection in sputum and BALF were compared. Odds ratios and 95% confidence intervals were used to assess variables t

SUBMITTER: Liu X 

PROVIDER: S-EPMC5868051 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature