Nanoelectronic Coating Enabled Versatile Multifunctional Neural Probes.

ABSTRACT: Brain function can be best studied by simultaneous measurements and modulation of the multifaceted signaling at the cellular scale. Extensive efforts have been made to develop multifunctional neural probes, typically involving highly specialized fabrication processes. Here, we report a novel multifunctional neural probe platform realized by applying ultrathin nanoelectronic coating (NEC) on the surfaces of conventional microscale devices such as optical fibers and micropipettes. We fabricated the NECs by planar photolithography techniques using a substrate-less and multilayer design, which host arrays of individually addressed electrodes with an overall thickness below 1 μm. Guided by an analytic model and taking advantage of the surface tension, we precisely aligned and coated the NEC dev

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC5869028 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature