Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report.

ABSTRACT:

Purpose

To assess the 5-year progression from unilateral to bilateral age-related macular degeneration (AMD) and associated risk factors.

Design

Pooled data analyses of three prospective population-based cohorts, the Blue Mountains Eye Study, Beaver Dam Eye Study and Rotterdam Study.

Methods

Retinal photography and interview with comprehensive questionnaires were conducted at each visit of three studies. AMD was assessed following the modified Wisconsin AMD grading protocol. Progression to bilateral any (early and late) or late AMD was assessed among participants with unilateral involvement only. Factors associated with the progression were assessed using logistic regression models while simultaneously adjusting for other significant risk factors.

Results

In an

SUBMITTER: Joachim N 

PROVIDER: S-EPMC5869687 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature