Prognostic Significance of Serum Inflammatory Markers in Gastric Cancer.

ABSTRACT: BACKGROUND:The aim of this study was to assess the relative prognostic value of biomarkers to measure the systemic inflammatory response (SIR) and improve prognostic modeling in a cohort of patients undergoing potentially curative surgery for gastric adenocarcinoma. The hypothesis was that a single SIR biomarker would be associated with the most prognostic value. METHODS:Consecutive 331 patients undergoing surgery for gastric cancer between 2004 and 2016 within a regional UK cancer network were identified. Serum measurements of hemoglobin, C-reactive protein, albumin, modified Glasgow Prognostic Score, and differential white cell counts were obtained before surgery, and correlated with histopathological factors (pTNM stage, differentiation, and vascular invasion) and survival. Primary outc

SUBMITTER: Powell AGMT 

PROVIDER: S-EPMC5869874 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature