Task-relevant brain networks identified with simultaneous PET/MR imaging of metabolism and connectivity.

ABSTRACT: Except for task-specific functional MRI, the vast majority of imaging studies assessed human brain function at resting conditions. However, tracking task-specific neuronal activity yields important insight how the brain responds to stimulation. We specifically investigated changes in glucose metabolism, functional connectivity and white matter microstructure during task performance using several recent methodological advancements. Opening the eyes and right finger tapping had elicited an increased glucose metabolism in primary visual and motor cortices, respectively. Furthermore, a decreased metabolism was observed in the regions of the default mode network, which allowed absolute quantification of commonly described deactivations during cognitive tasks. These brain regions showed widespre

SUBMITTER: Hahn A 

PROVIDER: S-EPMC5869947 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature