Effects of Dangguixu-san on acute lateral ankle sprain: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Ankle sprain is a common musculoskeletal injury. In Korean medicine, blood stasis is thought to be the main cause of pain and swelling in patients with ankle sprain. Dangguixu-san (DS), a herbal extract, is widely used in Korean medicine for the treatment of traumatic ecchymosis and pain by promoting blood circulation and relieving blood stasis. However, the effects of DS on ankle sprain have not been evaluated in a randomized clinical trial. Here, we describe the protocol for a randomized controlled trial that will evaluate the efficacy and safety of DS for the treatment of ankle sprain.

Methods/design

In this randomized, double-blinded, placebo-controlled, parallel-arm clinical trial with a 1:1 allocation ratio, participants (n = 48) with acute lateral ankle spr

SUBMITTER: Kim JH 

PROVIDER: S-EPMC5870178 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature