Exposure to hazardous air pollutants and risk of incident breast cancer in the nurses' health study II.

ABSTRACT:

Background

Findings from a recent prospective cohort study in California suggested increased risk of breast cancer associated with higher exposure to certain carcinogenic and estrogen-disrupting hazardous air pollutants (HAPs). However, to date, no nationwide studies have evaluated these possible associations. Our objective was to examine the impacts of mammary carcinogen and estrogen disrupting HAPs on risk of invasive breast cancer in a nationwide cohort.

Methods

We assigned HAPs from the US Environmental Protection Agency's 2002 National Air Toxics Assessment to 109,239 members of the nationwide, prospective Nurses' Health Study II (NHSII). Risk of overall invasive, estrogen receptor (ER)-positive (ER+), and ER-negative (ER-) breast cancer with increasing quartiles of exp

SUBMITTER: Hart JE 

PROVIDER: S-EPMC5870204 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature