Alignment of dynamic networks.

ABSTRACT:

Motivation

Network alignment (NA) aims to find a node mapping that conserves similar regions between compared networks. NA is applicable to many fields, including computational biology, where NA can guide the transfer of biological knowledge from well- to poorly-studied species across aligned network regions. Existing NA methods can only align static networks. However, most complex real-world systems evolve over time and should thus be modeled as dynamic networks. We hypothesize that aligning dynamic network representations of evolving systems will produce superior alignments compared to aligning the systems' static network representations, as is currently done.

Results

For this purpose, we introduce the first ever dynamic NA method, DynaMAGNA ++. This proof-of-concept dynam

SUBMITTER: Vijayan V 

PROVIDER: S-EPMC5870706 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature