Moran's I quantifies spatio-temporal pattern formation in neural imaging data.

ABSTRACT:

Motivation

Neural activities of the brain occur through the formation of spatio-temporal patterns. In recent years, macroscopic neural imaging techniques have produced a large body of data on these patterned activities, yet a numerical measure of spatio-temporal coherence has often been reduced to the global order parameter, which does not uncover the degree of spatial correlation. Here, we propose to use the spatial autocorrelation measure Moran's I, which can be applied to capture dynamic signatures of spatial organization. We demonstrate the application of this technique to collective cellular circadian clock activities measured in the small network of the suprachiasmatic nucleus (SCN) in the hypothalamus.

Results

We found that Moran's I is a practical quantitative measur

SUBMITTER: Schmal C 

PROVIDER: S-EPMC5870747 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature