Use of adjuvant chemotherapy in patients with stage III colon cancer in Puerto Rico: A population-based study.

ABSTRACT:

Objective

This study aims to examine factors associated with the use of adjuvant chemotherapy and the use of oxaliplatin after curative resection in stage III colon cancer patients and assesses the effect of their use in three-year survival.

Methods

This retrospective cohort study was conducted using Puerto Rico Central Cancer Registry-Health Insurance Linkage Database. The study cohort consisted of stage III colon cancer patients with a curative surgery in the period 2008-2012. Multivariate logistic regression was used to estimate adjusted odds ratios. Kaplan-Meier methods and Cox proportional hazards models were used to assess the association between adjuvant chemotherapy and oxaliplatin use and overall survival and risk of death, respectively.

Results

Overall, 75%

SUBMITTER: Ortiz-Ortiz KJ 

PROVIDER: S-EPMC5870969 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature