Pain and functional trajectories in symptomatic knee osteoarthritis over up to 12 weeks of exercise exposure.

ABSTRACT:

Objective

Exercise is the recommended treatment for knee osteoarthritis (OA). However, heterogeneous patterns in treatment response are poorly understood. Our purpose was to identify pain and functional trajectories from exercise interventions in knee OA, and to determine their association with baseline factors.

Methods

Prospective cohort of 171 participants (mean age 61 years; BMI 32 kg/m², 71% female; 57% white) with symptomatic knee OA from a randomized trial comparing 12-week Tai Chi and Physical Therapy. We analyzed weekly Western Ontario and McMaster Osteoarthritis Index (WOMAC) pain (0-500) and function (0-1700) scores using group-based trajectory models. Associations between baseline factors and trajectories were examined using multinomial logistic regress

SUBMITTER: Lee AC 

PROVIDER: S-EPMC5871586 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature