Association between periconceptional weight loss and maternal and neonatal outcomes in obese infertile women.

ABSTRACT:

Background

Obesity in women of reproductive age has deleterious effects on reproductive and offspring health. In this study, we aimed to evaluate the association between the magnitude of periconceptional body-mass index (BMI) change and maternal and neonatal outcomes in obese infertile women who participated in the LIFEstyle study. The LIFEstyle study was a randomized controlled trial, evaluating if a six-month lifestyle intervention program prior to infertility treatment in obese infertile women improved birth rates, compared to prompt infertility treatment.

Methods and findings

This is an exploratory post hoc analysis of the LIFEstyle study. We recorded periconceptional BMI change in women with an ongoing pregnancy, pooling data of all women, regardless of randomization ar

SUBMITTER: van Oers AM 

PROVIDER: S-EPMC5873932 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature