Investigating Colonization of the Healthy Adult Gastrointestinal Tract by Fungi.

ABSTRACT: A wide diversity of fungi have been detected in the human gastrointestinal (GI) tract with the potential to provide or influence important functions. However, many of the fungi most commonly detected in stool samples are also present in food or the oral cavity. Therefore, to recognize which gut fungi are likely to have a sustained influence on human health, there is a need to separate transient members of the GI tract from true colonizers. To identify colonizing fungi, the eukaryotic rRNA operon's second internal transcribed spacer (ITS2) was sequenced from the stool, saliva, and food of healthy adults following consumption of different controlled diets. Unlike most bacterial 16S rRNA genes, the only fungal ITS2 operational taxonomic units (OTUs) detected in stool DNA across multiple diets

SUBMITTER: Auchtung TA 

PROVIDER: S-EPMC5874442 | biostudies-literature | 2018 Mar-Apr

REPOSITORIES: biostudies-literature