Multi-isocentric 4π volumetric-modulated arc therapy approach for head and neck cancer.

ABSTRACT:

Objectives

To explore the feasibility of multi-isocentric 4π volumetric-modulated arc therapy (MI4π-VMAT) for the complex targets of head and neck cancers.

Methods

Twenty-five previously treated patients of HNC underwent re-planning to improve the dose distributions with either coplanar VMAT technique (CP-VMAT) or noncoplanar MI4π-VMAT plans. The latter, involving 3-6 noncoplanar arcs and 2-3 isocenters were re-optimized using the same priorities and objectives. Dosimetric comparison on standard metrics from dose-volume histograms was performed to appraise relative merits of the two techniques. Pretreatment quality assurance was performed with IMRT phantoms to assess deliverability and accuracy of the MI4π-VMAT plans. The gamma agreement index (GAI) analysis with criteria of

SUBMITTER: Subramanian VS 

PROVIDER: S-EPMC5874945 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature