Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC5874986 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Li Chao C Hu Xiaolu X Lu Jianyang J Mao Xiaoxia X Xiang Yang Y Shu Yongqian Y Li Genxi G
Chemical science 20171128 4
Here we report a robust and sensitive DNA nanostructure-based electrochemical (E-nanoDNA) sensor that utilizes tetrahedral DNA nanostructures (TDNs) as an interfacial probe to detect biomolecules in a single-step procedure. In this study, we have firstly demonstrated that the use of TDNs can significantly suppress electrochemical background signals compared to traditional linear DNA probes upon introduction of base mismatches in the edges of TDNs. After further optimization of the two functional ...[more]