Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal.

ABSTRACT: We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance.

SUBMITTER: Isidro J 

PROVIDER: S-EPMC5875251 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature