Association Between Hemodynamic Markers of Pulmonary Hypertension and Outcomes in Heart Failure With Preserved Ejection Fraction.

ABSTRACT:

Importance

Heart failure with preserved ejection fraction (HFpEF) is highly prevalent, yet there are no specific therapies, possibly due to phenotypic heterogeneity. The development of pulmonary hypertension (PH) in patients with HFpEF is considered a high-risk phenotype in need of targeted therapies, but there have been limited hemodynamic and outcomes data.

Objective

To identify the hemodynamic characteristics and outcomes of PH-HFpEF.

Design, setting, and participants

Cohort study of participants who had a right heart catheterization from January 2005 to September 2012 (median [interquartile range] follow-up time, 1578 [554-2513] days) were analyzed. Hemodynamic catheterization data was linked to the clinical data repository of all inpatient and outpatient encounte

SUBMITTER: Vanderpool RR 

PROVIDER: S-EPMC5875307 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature