Association of Prenatal Ultrasonography and Autism Spectrum Disorder.

ABSTRACT:

Importance

The prevalence of autism spectrum disorder (ASD) has been increasing rapidly, with current estimates of 1 in 68 children affected. Simultaneously, use of prenatal ultrasonography has increased substantially, with limited investigation into its safety and effects on brain development. Animal studies have demonstrated that prenatal ultrasonography can adversely affect neuronal migration.

Objective

To quantify prenatal ultrasound exposure by the frequency, timing, duration, and strength of ultrasonographic scans in children with later ASD, developmental delay, and typical development.

Design, setting, and participants

This case-control study included 107 patients with ASD, 104 control individuals with developmental delay, and 209 controls with typical developm

SUBMITTER: Rosman NP 

PROVIDER: S-EPMC5875374 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature