Ethnic differences in the progression of chronic kidney disease and risk of death in a UK diabetic population: an observational cohort study.

ABSTRACT:

Objective

To determine ethnic differences in the progression of chronic kidney disease (CKD) and risk of end-stage renal failure (ESRF) and death in adults with type 2 diabetes mellitus (T2DM), and to identify predictors of rapid renal decline.

Design

Observational community-based cohort study undertaken from 2006 to 2016 with nested case-control study.

Setting

135 inner London primary care practices contributing to the east London Database.

Participants

General practice-registered adults aged 25-85 years with established T2DM and CKD at baseline.

Outcomes

The annual rate of renal decline was compared between white, south Asian and black groups, and stratified by proteinuria and raised blood pressure (BP) at baseline. Predictors of rapid renal decline we

SUBMITTER: Mathur R 

PROVIDER: S-EPMC5875688 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature