Investigation of the seasonal microbiome of Anopheles coluzzii mosquitoes in Mali.

ABSTRACT: The poorly understood mechanisms of dry season persistence of Anopheles spp. mosquitoes through the dry season in Africa remain a critical gap in our knowledge of Plasmodium disease transmission. While it is thought that adult mosquitoes remain in a dormant state throughout this seven-month dry season, the nature of this state remains unknown and has largely not been recapitulated in laboratory settings. To elucidate possible connections of this state with microbial composition, the whole body microbiomes of adult mosquitoes in the dry and wet seasons in two locations of Mali with varying water availability were compared by sequencing the 16S ribosomal RNA gene. These locations were a village near the Niger River with year-round water sources (N'Gabakoro, "riparian"), and a typical Sahelia

SUBMITTER: Krajacich BJ 

PROVIDER: S-EPMC5875798 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature