Multinational Home Use of Closed-Loop Control Is Safe and Effective.

ABSTRACT:

Objective

To evaluate the efficacy of a portable, wearable, wireless artificial pancreas system (the Diabetes Assistant [DiAs] running the Unified Safety System) on glucose control at home in overnight-only and 24/7 closed-loop control (CLC) modes in patients with type 1 diabetes.

Research design and methods

At six clinical centers in four countries, 30 participants 18-66 years old with type 1 diabetes (43% female, 96% non-Hispanic white, median type 1 diabetes duration 19 years, median A1C 7.3%) completed the study. The protocol included a 2-week baseline sensor-augmented pump (SAP) period followed by 2 weeks of overnight-only CLC and 2 weeks of 24/7 CLC at home. Glucose control during CLC was compared with the baseline SAP.

Results

Glycemic control parameters for ov

SUBMITTER: Anderson SM 

PROVIDER: S-EPMC5876016 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature