Outcomes of persistent pulmonary hypertension following transcatheter aortic valve replacement.

ABSTRACT:

Objectives

To determine the prevalence and factors associated with persistent pulmonary hypertension (PH) following transcatheter aortic valve replacement (TAVR) and its relationship with long-term mortality.

Methods

Consecutive patients who underwent TAVR from July 2011 through January 2016 were studied. The prevalence of baseline PH (mean pulmonary artery pressure ≥25 mm Hg on right heart catheterisation) and the prevalence and the predictors of persistent≥moderate PH (pulmonary artery systolic pressure (PASP)>45 mm Hg on 1 month post-TAVR transthoracic Doppler echocardiography) were collected. Cox models quantified the effect of persistent PH on subsequent mortality while adjusting for confounders.

Results

Of the 407 TAVR patients, 273 (67%) had PH at baseline. Of

SUBMITTER: Masri A 

PROVIDER: S-EPMC5876149 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature