Highly Elastic Biodegradable Single-Network Hydrogel for Cell Printing.

ABSTRACT: Cell printing is becoming a common technique to fabricate cellularized printed scaffold for biomedical application. There are still significant challenges in soft tissue bioprinting using hydrogels, which requires live cells inside the hydrogels. Moreover, the resilient mechanical properties from hydrogels are also required to mechanically mimic the native soft tissues. Herein, we developed a visible-light cross-linked, single-network, biodegradable hydrogel with high elasticity and flexibility for cell printing, which is different from previous highly elastic hydrogel with double-network and two components. The single-network hydrogel using only one stimulus (visible light) to trigger gelation can greatly simplify the cell printing process. The obtained hydrogels possessed high elasticity

SUBMITTER: Xu C 

PROVIDER: S-EPMC5876623 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature