Vascular Malformations and Health-Related Quality of Life: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Patients with vascular malformations (VAMs) and vascular overgrowth syndromes have lower health-related quality of life (HRQoL) attributable to social stigmatization, poor mental health, severity, and pain. However, the factors that contribute to this decreased HRQoL are not clear.

Objective

To perform a systematic review and meta-analysis of studies that used validated HRQoL instruments to compare the HRQoL of persons with VAMs with the US general population.

Data sources

A comprehensive search was performed in MEDLINE, Embase, PsycINFO, CINAHL, and Scopus from 1946 to March 31, 2017, with the consultation of an experienced librarian.

Study selection

All VAM studies with validated HRQoL instruments published in the English language were included. Ca

SUBMITTER: Nguyen HL 

PROVIDER: S-EPMC5876813 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature