Association of Vitamin A Supplementation With Disease Course in Children With Retinitis Pigmentosa.

ABSTRACT:

Importance

While oral vitamin A supplementation is considered to potentially slow loss of retinal function in adults with retinitis pigmentosa and normal liver function, little data from children with this disease are available.

Objective

To compare disease courses in children with retinitis pigmentosa taking or not taking vitamin A supplementation.

Design, setting, and participants

Retrospective, nonrandomized comparison of vitamin A and control cohorts followed up for a mean of 4 to 5 years by the Electroretinography Service of the Massachusetts Eye and Ear Infirmary. The study included children with different genetic types of typical retinitis pigmentosa: 55 taking vitamin A and 25 not taking vitamin A. The dates for patient evaluations ranged from June 1976 to Jul

SUBMITTER: Berson EL 

PROVIDER: S-EPMC5876883 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature