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Standardization of in vitro assays to evaluate the activity of polyherbal siddha formulations against Chikungunya virus infection.


ABSTRACT: Chikungunya, a viral fever caused by Aedes mosquito results in extreme morbidity in affected individuals and is a major public health concern in India. Currently, modern vaccines or formulations prescribed by physicians can only provide symptomatic relief for the pyretic and post pyretic phase of the disease. Siddha practitioners follows strict medical regimen based on traditional Indian knowledge/concepts to treat Chikungunya with considerable results. The current study was undertaken to standardize assays for the study of these siddha formulations and to check their efficacy and potential mode of action as antivirals for Chikungunya virus infection in in vitro system. Although, siddha practitioners follow a regime containing 4-6 formulations, of these Brahmanandha bairavam mathirai, a pa

SUBMITTER: Jain J 

PROVIDER: S-EPMC5877857 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature