Oropharyngeal dysphagia profiles in individuals with oculopharyngeal muscular dystrophy.

ABSTRACT:

Background

Although dysphagia represents a hallmark manifestation of oculopharyngeal muscular dystrophy (OPMD), limited knowledge exists regarding the underlying nature of oropharyngeal swallowing impairments in this patient population. We aimed to delineate global pharyngeal dysphagia profiles in OPMD and identify the prevalence and physiologic associations of impairments in swallowing safety and efficiency.

Methods

Twenty-two individuals with OPMD completed a videofluoroscopic swallowing evaluation. Blinded raters completed validated scales of global dysphagia (dynamic imaging grade of swallowing toxicity, DIGEST), efficiency (normalized residue ratio scale, NRRS), and safety (penetration-aspiration scale, PAS). Degree of laryngeal vestibule closure and aspiration events w

SUBMITTER: Tabor LC 

PROVIDER: S-EPMC5878694 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature