CODIFI (Concordance in Diabetic Foot Ulcer Infection): a cross-sectional study of wound swab versus tissue sampling in infected diabetic foot ulcers in England.

ABSTRACT:

Objective

To determine the extent of agreement and patterns of disagreement between wound swab and tissue samples in patients with an infected diabetic foot ulcer (DFU).

Design

Multicentre, prospective, cross-sectional study.

Setting

Primary and secondary care foot ulcer/diabetic outpatient clinics and hospital wards across England.

Participants

Inclusion criteria: consenting patients aged ≥18 years; diabetes mellitus; suspected infected DFU.

Exclusion criteria

clinically inappropriate to take either sample.

Interventions

Wound swab obtained using Levine's technique; tissue samples collected using a sterile dermal curette or scalpel.

Outcome measures

Coprimary: reported presence, and number, of pathogens per sample; prevalence of resistance

SUBMITTER: Nelson A 

PROVIDER: S-EPMC5879729 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature