Voltage adjustment improves rigidity and tremor in Parkinson's disease patients receiving deep brain stimulation.

ABSTRACT: Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson's disease. Programming of the stimulation parameters is important for maintaining the efficacy of deep brain stimulation. Voltage is considered to be the most effective programming parameter. The present study is a retrospective analysis of six patients with Parkinson's disease (four men and two women, aged 37-65 years), who underwent bilateral deep brain stimulation of the subthalamic nucleus at the First Affiliated Hospital of Sun Yat-sen University, China, and who subsequently adjusted only the stimulation voltage. We evaluated motor symptom severity using the Unified Parkinson's Disease Rating Scale Part III, symptom progression using the Hoehn and Yahr sc

SUBMITTER: Xu SH 

PROVIDER: S-EPMC5879909 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature