Low-protein diet for conservative management of chronic kidney disease: a systematic review and meta-analysis of controlled trials.

ABSTRACT:

Background

Recent data pose the question whether conservative management of chronic kidney disease (CKD) by means of a low-protein diet can be a safe and effective means to avoid or defer transition to dialysis therapy without causing protein-energy wasting or cachexia. We aimed to systematically review and meta-analyse the controlled clinical trials with adequate participants in each trial, providing rigorous contemporary evidence of the impact of a low-protein diet in the management of uraemia and its complications in patients with CKD.

Methods

We searched MEDLINE (PubMed) and other sources for controlled trials on CKD to compare clinical management of CKD patients under various levels of dietary protein intake or to compare restricted protein intake with other interventio

SUBMITTER: Rhee CM 

PROVIDER: S-EPMC5879959 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature