Characterizing cross-subject spatial interaction patterns in functional magnetic resonance imaging studies: A two-stage point-process model.

ABSTRACT: We develop a two-stage spatial point process model that introduces new characterizations of activation patterns in multisubject functional Magnetic Resonance Imaging (fMRI) studies. Conventionally multisubject fMRI methods rely on combining information across subjects one voxel at a time in order to identify locations of peak activation in the brain. The two-stage model that we develop here addresses shortcomings of standard methods by explicitly modeling the spatial structure of functional signals and recognizing that corresponding cross-subject functional signals can be spatially misaligned. In our first stage analysis, we introduce a marked spatial point process model that captures the spatial features of the functional response and identifies a configuration of activation units for eac

SUBMITTER: Lee A 

PROVIDER: S-EPMC5880034 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature