Comparative genome analysis of 24 bovine-associated Staphylococcus isolates with special focus on the putative virulence genes.

ABSTRACT: Non-aureus staphylococci (NAS) are most commonly isolated from subclinical mastitis. Different NAS species may, however, have diverse effects on the inflammatory response in the udder. We determined the genome sequences of 20 staphylococcal isolates from clinical or subclinical bovine mastitis, belonging to the NAS species Staphylococcus agnetis, S. chromogenes, and S. simulans, and focused on the putative virulence factor genes present in the genomes. For comparison we used our previously published genome sequences of four S. aureus isolates from bovine mastitis. The pan-genome and core genomes of the non-aureus isolates were characterized. After that, putative virulence factor orthologues were searched in silico. We compared the presence of putative virulence

SUBMITTER: Avall-Jaaskelainen S 

PROVIDER: S-EPMC5880176 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature