Cardiovascular Outcomes after a Respiratory Tract Infection among Adults with Non-Cystic Fibrosis Bronchiectasis: A General Population-based Study.

ABSTRACT:

Rationale

Studies suggest that adults with bronchiectasis are at increased risk of cardiovascular comorbidities.

Objectives

We aimed to quantify the relative risk of incident cardiovascular events after a respiratory tract infection among adults with bronchiectasis.

Methods

Using UK electronic primary care records, we conducted a within-person comparison using the self-controlled case series method. We calculated the relative risk of first-time cardiovascular events (either first myocardial infarction or stroke) after a respiratory tract infection compared with the individual's baseline risk.

Results

Our cohort consisted of 895 adult men and women with non-cystic fibrosis bronchiectasis with a first myocardial infarction or stroke and at least one respiratory t

SUBMITTER: Navaratnam V 

PROVIDER: S-EPMC5880522 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature