Risk of stroke and bleeding in patients with heart failure and chronic kidney disease: a nationwide cohort study.

ABSTRACT:

Aims

The aim of this study was to assess the prognostic value of chronic kidney disease (CKD) in relation to ischaemic stroke, intracranial haemorrhage, major bleeding, and all-cause death in heart failure patients without atrial fibrillation.

Methods and results

In this observational cohort study, heart failure patients without atrial fibrillation were identified using Danish nationwide registries. Risk of stroke, major haemorrhage, and death were calculated after 1 and 5 years to compare patients with and without CKD, ±dialysis [dialysis: CKD with renal replacement therapy (CKD-RRT); no dialysis: CKD-no RRT]. A total of 43 199 heart failure patients were included, among which 0.8% had CKD-RRT and 5.9% had CKD-no RRT. When compared with heart failure patients without CKD, b

SUBMITTER: Melgaard L 

PROVIDER: S-EPMC5880668 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature