FRAX- vs. T-score-based intervention thresholds for osteoporosis.

ABSTRACT: Many current guidelines for the assessment of osteoporosis, including those in Kuwait, initiate fracture risk assessment in men and women using BMD T-score thresholds. We compared the Kuwaiti guidelines with FRAX-based age-dependent intervention thresholds equivalent to that in women with a prior fragility fracture. FRAX-based intervention thresholds identified women at higher fracture probability than fixed T-score thresholds, particularly in the elderly.

Purpose

A FRAX® model been recently calibrated for Kuwait, but guidance is needed on how to utilise fracture probabilities in the assessment and treatment of patients.

Methods

We compared age-specific fracture probabilities, equivalent to women with no clinical risk factors and a prior fragility fracture (without BMD), with

SUBMITTER: Johansson H 

PROVIDER: S-EPMC5881885 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature