Racial-ethnic differences in midtrimester maternal serum levels of angiogenic and antiangiogenic factors.

ABSTRACT:

Background

Little is known about racial-ethnic differences in the distribution of maternal serum levels of angiogenic and antiangiogenic factors and their associations with early-onset preeclampsia.

Objective

We sought to investigate the distribution of midtrimester maternal serum levels of placental growth factor, soluble endoglin, and soluble vascular endothelial growth factor receptor 1 and their associations with early-onset preeclampsia in whites, Hispanics, and blacks.

Study design

A population-based nested case-control design was used to identify cases and controls of white, Hispanic, and black origin from a 2000 through 2007 live-birth cohort in 5 southern California counties. Cases included 197 women (90 whites, 67 Hispanics, and 40 blacks) with early-onset p

SUBMITTER: Yang J 

PROVIDER: S-EPMC5881897 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature