Spirometric impairments, cardiovascular outcomes, and noncardiovascular death in older persons.

ABSTRACT:

Background

In prior work involving older persons, the reported associations of spirometric impairments with cardiovascular outcomes may have been confounded by age-related changes in lung function. Hence, using more age-appropriate spirometric criteria from the Global Lung Function Initiative (GLI), we have evaluated the associations of spirometric impairments, specifically restrictive-pattern and airflow-obstruction, with cardiovascular death (CV-death) and hospitalization (CV-hospitalization). In these analyses, we also evaluated the competing outcome of noncardiovascular death (nonCV-death) and calculated measures of relative and absolute risk.

Methods

Our study sample was drawn from the Cardiovascular Health Study (CHS), including 4232 community-dwelling white persons ag

SUBMITTER: Vaz Fragoso CA 

PROVIDER: S-EPMC5881905 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature